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Motion compensated renal diffusion weighted imaging
Author(s) -
McTavish Sean,
Van Anh T.,
Peeters Johannes M.,
Weiss Kilian,
Makowski Marcus R.,
Braren Rickmer F.,
Karampinos Dimitrios C.
Publication year - 2023
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.29433
Subject(s) - waveform , effective diffusion coefficient , respiratory system , respiratory monitoring , diffusion , kidney , medicine , nuclear medicine , physics , magnetic resonance imaging , radiology , voltage , quantum mechanics , thermodynamics
Purpose To assess the effect of respiratory motion and cardiac driven pulsation in renal DWI and to examine asymmetrical velocity‐compensated diffusion encoding waveforms for robust ADC mapping in the kidneys. Methods The standard monopolar Stejskal‐Tanner pulsed gradient spin echo (pgse) and the asymmetric bipolar velocity‐compensated (asym‐vc) diffusion encoding waveforms were used for coronal renal DWI at 3T. The robustness of the ADC quantification in the kidneys was tested with the aforementioned waveforms in respiratory‐triggered and breath‐held cardiac‐triggered scans at different trigger delays in 10 healthy subjects. Results The pgse waveform showed higher ADC values in the right kidney at short trigger delays in comparison to longer trigger delays in the respiratory triggered scans when the diffusion gradient was applied in the feet‐head (FH) direction. The coefficient of variation over all respiratory trigger delays, averaged over all subjects was 0.15 for the pgse waveform in the right kidney when diffusion was measured in the FH direction; the corresponding coefficient of variation for the asym‐vc waveform was 0.06. The effect of cardiac driven pulsation was found to be small in comparison to the effect of respiratory motion. Conclusion Short trigger delays in respiratory‐triggered scans can cause higher ADC values in comparison to longer trigger delays in renal DWI, especially in the right kidney when diffusion is measured in the FH direction. The asym‐vc waveform can reduce ADC variation due to respiratory motion in respiratory‐triggered scans at the cost of reduced SNR compared to the pgse waveform.