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Conditional safety margins for less conservative peak local SAR assessment: A probabilistic approach
Author(s) -
Meliadò Ettore Flavio,
Sbrizzi Alessandro,
van den Berg Cornelis A. T.,
Steensma Bart R.,
Luijten Peter R.,
Raaijmakers Alexander J. E.
Publication year - 2020
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.28335
Subject(s) - margin (machine learning) , probability density function , computer science , probabilistic logic , synthetic aperture radar , stability (learning theory) , function (biology) , artificial intelligence , statistics , algorithm , mathematics , machine learning , evolutionary biology , biology
Purpose The introduction of a linear safety factor to address peak local specific absorption rate (pSAR 10g ) uncertainties (eg, intersubject variation, modeling inaccuracies) bears one considerable drawback: It often results in over‐conservative scanning constraints. We present a more efficient approach to define a variable safety margin based on the conditional probability density function of the effectively obtained pSAR 10g value, given the estimated pSAR 10g value. Methods The conditional probability density function can be estimated from previously simulated data. A representative set of true and estimated pSAR 10g samples was generated by means of our database of 23 subject‐specific models with an 8‐fractionated dipole array for prostate imaging at 7 T. The conditional probability density function was calculated for each possible estimated pSAR 10g value and used to determine the corresponding safety margin with an arbitrary low probability of underestimation. This approach was applied to five state‐of‐the‐art local SAR estimation methods, namely: (1) using just the generic body model “Duke”; (2) using our model library to assess the maximum pSAR 10g value over all models; (3) using the most representative “local SAR model”; (4) using the five most representative local SAR models; and (5) using a recently developed deep learning–based method. Results Compared with the more conventional safety factor, the conditional safety‐margin approach results in lower (up to 30%) mean overestimation for all investigated local SAR estimation methods. Conclusion The proposed probabilistic approach for pSAR 10g correction allows more accurate local SAR assessment with much lower overestimation, while a predefined level of underestimation is accepted (eg, 0.1%).

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