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Magnetic resonance fingerprinting for simultaneous renal T 1 and T 2 * mapping in a single breath‐hold
Author(s) -
Hermann Ingo,
ChaconCaldera Jorge,
Brumer Irène,
Rieger Benedikt,
Weingärtner Sebastian,
Schad Lothar R.,
Zöllner Frank G.
Publication year - 2020
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.28160
Subject(s) - imaging phantom , magnetic resonance imaging , standard deviation , coronal plane , orientation (vector space) , nuclear medicine , nuclear magnetic resonance , artificial intelligence , pattern recognition (psychology) , mathematics , computer science , physics , medicine , radiology , statistics , geometry
Purpose To evaluate the use of magnetic resonance fingerprinting (MRF) for simultaneous quantification of T 1 and T 2 ∗ in a single breath‐hold in the kidneys. Methods The proposed kidney MRF sequence was based on MRF echo‐planar imaging. Thirty‐five measurements per slice and overall 4 slices were measured in 15.4 seconds. Group matching was performed for in‐line quantification of T 1 and T 2 ∗ . Images were acquired in a phantom and 8 healthy volunteers in coronal orientation. To evaluate our approach, region of interests were drawn in the kidneys to calculate mean values and standard deviations of the T 1 and T 2 ∗ times. Precision was calculated across multiple repeated MRF scans. Gaussian filtering is applied on baseline images to improve SNR and match stability. ResultsT 1 and T 2 ∗ times acquired with MRF in the phantom showed good agreement with reference measurements and conventional mapping methods with deviations of less than 5% for T 1 and less than 10% for T 2 ∗ . Baseline images in vivo were free of artifacts and relaxation times yielded good agreement with conventional methods and literature (deviationT 1 : 7 ± 4 % ,T 2 ∗ : 6 ± 3 % ). Conclusions In this feasibility study, the proposed renal MRF sequence resulted in accurate T 1 and T 2 ∗ quantification in a single breath‐hold.