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Magnetization transfer and frequency distribution effects in the SSFP ellipse
Author(s) -
Wood Tobias C.,
Teixeira Rui P. A. G.,
Malik Shaihan J.
Publication year - 2020
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.28149
Subject(s) - steady state free precession imaging , magnetization transfer , magnetization , monte carlo method , physics , nuclear magnetic resonance , flip angle , ellipse , statistics , mathematics , magnetic resonance imaging , magnetic field , medicine , quantum mechanics , astronomy , radiology
Purpose To demonstrate that quantitative magnetization transfer (qMT) parameters can be extracted from steady‐state free‐precession (SSFP) data with no external T 1 map or banding artifacts. Methods SSFP images with multiple MT weightings were acquired and qMT parameters fitted with a two‐stage elliptical signal model. Results Monte Carlo simulations and data from a 3T scanner indicated that most qMT parameters could be recovered with reasonable accuracy. Systematic deviations from theory were observed in white matter, consistent with previous literature on frequency distribution effects. Conclusions qMT parameters can be extracted from SSFP data alone, in a manner robust to banding artifacts, despite several confounds.