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A dual‐tuned 17 O/ 1 H head array for direct brain oximetry at 3 Tesla
Author(s) -
Lakshmanan Karthik,
Dehkharghani Seena,
Madelin Guillaume,
Brown Ryan
Publication year - 2020
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.28005
Subject(s) - nuclear magnetic resonance , physics , electromagnetic coil , sensitivity (control systems) , resolution (logic) , nuclear medicine , materials science , computer science , medicine , artificial intelligence , quantum mechanics , electronic engineering , engineering
Purpose To design and build a dual‐tuned 17 O/ 1 H coil for direct brain oximetry at 3T. Methods A dual‐tuned 17 O/ 1 H coil comprising 2 degenerate mode birdcage coils was constructed to facilitate high‐sensitivity 17 O and 1 H imaging. In vivo 17 O brain images were acquired in a healthy volunteer using a fermat looped orthogonally encoded trajectories sequence, together with high‐resolution structural brain 1 H images. Results Natural abundance 17 O images with a nominal resolution of 8 mm 3 were acquired in under 20 minutes exhibiting clear delineation of the physiological 17 O distribution. One‐millimeter isotropic 1 H structural brain images demonstrated excellent quality and anatomical detail using routine clinical imaging sequence parameters and parallel acceleration. Conclusion A dual‐tuned 17 O/ 1 H array was constructed to enable high‐sensitivity 17 O and 1 H imaging under standard clinical 3 T scanning conditions.