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Reducing the number of samples in spatiotemporal dMRI acquisition design
Author(s) -
Filipiak Patryk,
Fick Rutger,
Petiet Alexandra,
Santin Mathieu,
Philippe AnneCharlotte,
Lehericy Stephane,
Ciuciu Philippe,
Deriche Rachid,
Wassermann Demian
Publication year - 2019
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.27601
Subject(s) - diffusion mri , computer science , signal (programming language) , sampling (signal processing) , algorithm , representation (politics) , heuristic , artificial intelligence , diffusion , genetic algorithm , pattern recognition (psychology) , quality (philosophy) , magnetic resonance imaging , computer vision , machine learning , physics , medicine , filter (signal processing) , quantum mechanics , politics , law , radiology , programming language , thermodynamics , political science
Purpose Acquisition time is a major limitation in recovering brain white matter microstructure with diffusion magnetic resonance imaging. The aim of this paper is to bridge the gap between growing demands on spatiotemporal resolution of diffusion signal and the real‐world time limitations. The authors introduce an acquisition scheme that reduces the number of samples under adjustable quality loss. Methods Finding a sampling scheme that maximizes signal quality and satisfies given time constraints is NP‐hard. Therefore, a heuristic method based on genetic algorithm is proposed in order to find suboptimal solutions in acceptable time. The analyzed diffusion signal representation is defined in the q τ space, so that it captures both spacial and temporal phenomena. Results The experiments on synthetic data and in vivo diffusion images of the C57Bl6 wild‐type mouse corpus callosum reveal superiority of the proposed approach over random sampling and even distribution in the q τ space. Conclusions The use of genetic algorithm allows to find acquisition parameters that guarantee high signal reconstruction accuracy under given time constraints. In practice, the proposed approach helps to accelerate the acquisition for the use of q τ‐dMRI signal representation.