Premium
Simultaneous multi‐slice cardiac cine with Fourier‐encoded self‐calibration at 7 Tesla
Author(s) -
Rapacchi Stanislas,
Troalen Thomas,
Bentatou Zakarya,
Quemeneur Morgane,
Guye Maxime,
Bernard Monique,
Jacquier Alexis,
Kober Frank
Publication year - 2019
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.27593
Subject(s) - nuclear medicine , calibration , nuclear magnetic resonance , materials science , physics , biomedical engineering , medicine , quantum mechanics
Purpose To accelerate cardiac cine at 7 tesla using simultaneous multi‐slice (SMS) acquisition with self‐calibration to resolve misalignment between calibration and imaging data due to breathing motion. Methods A spoiled‐gradient echo cine sequence was modified with radiofrequency phase‐cycled SMS excitations. A Fourier encoding strategy was applied along the cardiac phase dimension to allow for slice untangling and split‐slice GRAPPA calibration. Split‐slice GRAPPA was coupled with regular GRAPPA (SMS‐GRAPPA) and L1‐SPIRiT (SMS‐L1SPIRiT) for image reconstruction. 3‐slice SMS cine MRI was evaluated in ten subjects against single‐slice cine MRI in terms of SNR and contrast‐to‐noise ratio and slice leakage. Results SNR decreased significantly from 10.1 ± 7.1 for single‐slice cine to 7.4 ± 2.8 for SMS‐GRAPPA ( P = 0.02) and was recovered to 9.0 ± 4.5 with SMS‐L1SPIRiT ( P = 0.02). Contrast to noise ratio decreased significantly from 14.5 ± 8.1 for single‐slice cine to 5.6 ± 3.6 for SMS‐GRAPPA ( P < 0.0001) and increased slightly but significantly back to 6.7 ± 4.4 for SMS‐L1SPIRiT ( P = 0.03). Specific absorption rate restrictions imposed a reduced nominal flip angle (−37 ± 7%, P = 0.02) for 3‐slice SMS excitations compared to single‐slice acquisitions. SMS slice leakage increased significantly from apex (8.6 ± 6.5 %) to base (13.1 ± 4.1 %, P = 0.03) in the left ventricle. Conclusion Three‐fold acceleration of cine at 7T was achieved using the proposed SMS technique. Fourier encoding self‐calibration and regularized image reconstruction enabled simultaneous acquisition of three slices without significant SNR decrease but significant CNR decrease linked to the reduced nominal excitation flip angle.