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In vivo phase imaging of human epiphyseal cartilage at 7 T
Author(s) -
Dymerska Barbara,
Bohndorf Klaus,
Schennach Paul,
Rauscher Alexander,
Trattnig Siegfried,
Robinson Simon D.
Publication year - 2018
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.26858
Subject(s) - magnetic resonance imaging , cartilage , knee cartilage , in vivo , nuclear magnetic resonance , quantitative susceptibility mapping , articular cartilage , gradient echo , phase imaging , susceptibility weighted imaging , magnetic susceptibility , biomedical engineering , anatomy , medicine , nuclear medicine , materials science , radiology , pathology , chemistry , biology , physics , osteoarthritis , alternative medicine , microbiology and biotechnology , microscopy , crystallography
Purpose To assess the potential clinical utility of in vivo susceptibility‐weighted imaging and quantitative susceptibility mapping of growth cartilage in the juvenile human knee at 7 T. Methods High‐resolution gradient‐echo images of the knees of six healthy children and adolescents aged 6 to 15 were acquired with a 28‐channel coil at 7 T. Phase images from the coils were combined using a short echo‐time reference scan method (COMPOSER). Results Veins oriented perpendicular to the static B 0 field appeared doubled in susceptibility‐weighted imaging, but not quantitative susceptibility mapping. Veins and layers in the cartilage were visible in all children up to the age of 13. Conclusions Phase imaging using susceptibility‐weighted imaging and quantitative susceptibility mapping allows the in vivo visualization of veins and layers in human growth cartilage. Magn Reson Med 79:2149–2155, 2018. © 2017 International Society for Magnetic Resonance in Medicine.