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Application of spin echoes in the regime of weak dephasing to T 1 ‐mapping of the lung
Author(s) -
Assländer Jakob,
Glaser Steffen J.,
Hennig Jürgen
Publication year - 2018
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.26719
Subject(s) - spin echo , dephasing , nuclear magnetic resonance , physics , scanner , fast spin echo , pulse sequence , multislice , excitation , magnetic resonance imaging , optics , condensed matter physics , medicine , radiology , quantum mechanics
Purpose This work presents an approach to mapping the entire lung's proton density and T 1 within a single breath‐hold and analyzes the apparent T 1 when exciting with a spin echo generating pulse in comparison to a standard gradient echo acquisition. Methods An inversion‐recovery SNAPSHOT‐FLASH sequence with a stack‐of‐stars k‐space readout with a golden angle increment was modified to use a spin echo generating radiofrequency‐pulse for excitation. Data of five volunteers were acquired on a 3T scanner and image reconstruction was performed by an iterative algorithm adopted from MR‐Fingerprinting. Results The feasibility of acquiring quantitative maps of the entire lung with a resolution of 5 × 5 × 10 mm within 7.5 s is demonstrated. It is shown that the proposed spin echo forming radiofrequency‐pulse increases the apparent proton density compared to a rectangular pulse. Further, the apparent T 1 is reduced in the spin echo case compared to the gradient echo sequence. Conclusion The proposed spin echo based method results in T 1 maps that are comparable to the ones that were acquired with ultra‐short echo time sequences elsewhere. The T 1 shortening is believed to originate from increased signal contributions of the extra vascular compartment, which has a shortT 2 ∗and T 1 . Magn Reson Med 79:960–967, 2018. © 2017 International Society for Magnetic Resonance in Medicine.