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Design and implementation of embedded 8‐channel receive‐only arrays for whole‐brain MRI and fMRI of conscious awake marmosets
Author(s) -
Papoti Daniel,
Yen Cecil ChernChyi,
Hung ChiaChun,
Ciuchta Jennifer,
Leopold David A.,
Silva Afonso C.
Publication year - 2017
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.26339
Subject(s) - marmoset , callithrix , electromagnetic coil , functional magnetic resonance imaging , computer science , radiofrequency coil , decoupling (probability) , neuroscience , psychology , physics , biology , engineering , paleontology , quantum mechanics , control engineering
Purpose The common marmoset (Callithrix jacchus) is a New World primate of increasing interest to neuroscience and in translational brain research. The present work describes the design and implementation of individualized 8‐channel receive‐only radiofrequency (RF) coil arrays that provide whole‐brain coverage and allow anatomical and functional MRI experiments in conscious, awake marmosets. Methods The coil arrays were designed with their elements embedded inside individualized restraint helmets. The size, geometry, and arrangement of the coil elements were optimized to allow whole‐brain coverage. Coil‐to‐coil decoupling was achieved by a combination of geometric decoupling and low input impedance preamplifiers. The performance of the embedded arrays was compared against that of one 8‐channel receive‐only array built to fit the external surface of the helmets. Results Three individualized helmets with embedded coil arrays were built for three marmosets. Whole‐brain coverage was achieved with high sensitivity extending over the entire cortex. Visual stimulation of conscious awake marmosets elicited robust BOLD fMRI responses in both primary and higher order visual areas of the occipitotemporal cortex. Conclusion The high sensitivity provided by embedded receive‐only coil arrays allows both anatomical and functional MRI data to be obtained with high spatial resolution in conscious, awake marmosets. Magn Reson Med 78:387–398, 2017. © 2016 International Society for Magnetic Resonance in Medicine