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A novel profile/view ordering with a non‐convex star shutter for high‐resolution 3D volumetric T 1 mapping under multiple breath‐holds
Author(s) -
Wang SuiCheng,
Patel Amit R.,
Tanaka Akiko,
Wang Hui,
Ota Takeyoshi,
Lang Roberto M.,
Carroll Timothy J.,
Kawaji Keigo
Publication year - 2017
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.26303
Subject(s) - shutter , star (game theory) , computer science , resolution (logic) , regular polygon , physics , artificial intelligence , computer vision , optics , mathematics , astrophysics , geometry
Purpose To examine a novel non‐convex star ordering/shutter for reducing the number of breath‐holds in cardiac three‐dimensional (3D) T 1 Mapping MRI with multiple breath‐holds. Methods A novel ordering, Non‐Convex Star (NCS) was designed to acquire 3D volumes in a modified look‐locker inversion recovery (MOLLI) T 1 mapping sequence to provide more spatial resolution and coverage in fewer breath‐holds. The proposed 3D‐MOLLI approach using NCS was first validated in two phantoms using artifact power (AP) measurement against the fully sampled phantom. This was followed by an in vivo study in seven swine, in which the T 1 values of the left ventricular (LV) myocardium divided into the American Heart Association (AHA) 16‐segment model was compared against the reference multislice two‐dimensional (2D) clinical reference and 3D volume without NCS breath‐hold reduction. Results NCS breath‐hold reduction yielded less AP compared with the matched SENSE accelerated phantom volume ( P < 0.0005), and was shown to be optimal at 25% fewer breath‐holds. Calculated T 1 values from 3D in vivo volumes with/without NCS were comparable in all AHA segments ( P = NS), whereas 3D‐NCS yielded significantly higher T 1 values than 2D at midslice of the LV myocardium in each AHA segment ( P < 0.05). Conclusion We successfully demonstrate the feasibility of the NCS approach for a 3D T 1 mapping acquisition requiring fewer breath‐holds. Magn Reson Med 77:2215–2224, 2017. © 2016 International Society for Magnetic Resonance in Medicine