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Free breathing three‐dimensional late gadolinium enhancement cardiovascular magnetic resonance using outer volume suppressed projection navigators
Author(s) -
Me Rajiv G.,
Miller G. Wilson,
Jeudy Jean,
Rajagopalan Sanjay,
Shin Taehoon
Publication year - 2017
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.26234
Subject(s) - magnetic resonance imaging , medicine , nuclear medicine , maximum intensity projection , artifact (error) , nuclear magnetic resonance , radiology , computer science , physics , angiography , computer vision
Purpose To develop a three‐dimensional, free‐breathing, late gadolinium enhancement (3D FB‐LGE) cardiovascular magnetic resonance (CMR) technique, and to compare it with clinically used two‐dimensional breath‐hold LGE (2D BH‐LGE). Methods The proposed 3D FB‐LGE method consisted of inversion preparation, inversion delay, fat saturation, outer volume suppression, one‐dimensional projection navigators, and a segmented stack of spirals acquisition. The 3D FB‐LGE and 2D BH‐LGE scans were performed on 29 cardiac patients. Qualitative analysis and quantitative analysis (in patients with scar) were performed. Results No significant differences were noted between the 3D FB‐LGE and 2D BH‐LGE data sets in terms of overall image quality score (2D: 4.69 ± 0.60 versus 3D: 4.55 ± 0.51, P = 0.46) and image artifact score (2D: 1.10 ± 0.31 versus 3D: 1.17 ± 0.38; P = 0.63). The average difference in fractional scar volume between the 3D and 2D methods was 1.9% (n = 5). Acquisition time was significantly shorter for the 3D FB‐LGE over 2D BH‐LGE by a factor of 2.83 ± 0.77 ( P < 0.0001). Conclusions The 3D FB‐LGE is a viable option for patients, particularly in acute settings or in patients who are unable to comply with breath‐hold instructions. Magn Reson Med 77:1533–1543, 2017. © 2016 International Society for Magnetic Resonance in Medicine