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Rapid acquisition of helium‐3 and proton three‐dimensional image sets of the human lung in a single breath‐hold using compressed sensing
Author(s) -
Qing Kun,
Altes Talissa A.,
Tustison Nicholas J.,
Feng Xue,
Chen Xiao,
Mata Jaime F.,
Miller G. Wilson,
de Lange Eduard E.,
Tobias William A.,
Cates Gordon D.,
Brookeman James R.,
Mugler John P.
Publication year - 2015
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.25499
Subject(s) - undersampling , compressed sensing , isotropy , image quality , iterative reconstruction , image resolution , computer science , scanner , acceleration , artificial intelligence , mathematics , physics , algorithm , computer vision , nuclear medicine , image (mathematics) , optics , medicine , classical mechanics
Purpose To develop and validate a method for acquiring helium‐3 ( 3 He) and proton ( 1 H) three‐dimensional (3D) image sets of the human lung with isotropic spatial resolution within a 10‐s breath‐hold by using compressed sensing (CS) acceleration, and to assess the fidelity of undersampled images compared with fully sampled images. Methods The undersampling scheme for CS acceleration was optimized and tested using 3 He ventilation data. Rapid 3D acquisition of both 3 He and 1 H data during one breath‐hold was then implemented, based on a balanced steady‐state free‐precession pulse sequence, by random undersampling of k‐space with reconstruction by means of minimizing the L1 norm and total variance. CS‐reconstruction fidelity was evaluated quantitatively by comparing fully sampled and retrospectively undersampled image sets. Results Helium‐3 and 1 H 3D image sets of the lung with isotropic 3.9‐mm resolution were acquired during a single breath‐hold in 12 s and 8 s using acceleration factors of 2 and 3, respectively. Comparison of fully sampled and retrospectively undersampled 3 He and 1 H images yielded mean absolute errors <10% and structural similarity indices >0.9. Conclusion By randomly undersampling k‐space and using CS reconstruction, high‐quality 3 He and 1 H 3D image sets with isotropic 3.9‐mm resolution can be acquired within an 8‐s breath‐hold. Magn Reson Med 74:1110–1115, 2015. © 2014 Wiley Periodicals, Inc.