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Phase contrast MRI with flow compensation view sharing
Author(s) -
Wang Da,
Shao Jiaxin,
Rapacchi Stanislas,
Middione Matthew J.,
Ennis Daniel B.,
Hu Peng
Publication year - 2015
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.25133
Subject(s) - imaging phantom , flow (mathematics) , contrast (vision) , flow measurement , compensation (psychology) , biomedical engineering , computer science , materials science , nuclear magnetic resonance , computer vision , nuclear medicine , medicine , mechanics , physics , psychology , psychoanalysis
Purpose To develop and evaluate a technique for accelerating phase contrast MRI (PC‐MRI) acquisitions without significant compromise in flow quantification accuracy. Methods PC‐MRI is commonly acquired using interleaved flow‐compensated (FC) and flow‐encoded (FE) echoes. We hypothesized that FC data, which represent background phase, do not change significantly over time. Therefore, we proposed to undersample the FC data and use an FC view sharing (FCVS) approach to synthesize a composite FC frame for each corresponding FE frame. FCVS was evaluated in a flow phantom and healthy volunteers and compared with a standard FC/FE PC‐MRI. Results The FCVS sequence resulted in an error of 0.0% for forward flow and 2.0% for reverse flow volume when compared with FC/FE PC‐MRI in a flow phantom. Measurements in the common carotid arteries showed that the FCVS method had −1.16 cm/s bias for maximum peak velocity and −0.019 mL bias in total flow, when compared with FC/FE with the same temporal resolution, but double the total acquisition time. These results represent ≤1.3% bias error in velocity and volumetric flow quantification. Conclusion FCVS can accelerate PC‐MRI acquisitions while maintaining flow and velocity measurement accuracy when there is limited temporal variation in the FC data. Magn Reson Med 73:505–513, 2015. © 2014 Wiley Periodicals, Inc.