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High spatial and temporal resolution dynamic contrast‐enhanced magnetic resonance angiography using compressed sensing with magnitude image subtraction
Author(s) -
Rapacchi Stanislas,
Han Fei,
Natsuaki Yutaka,
Kroeker Randall,
Plotnik Adam,
Lehrman Evan,
Sayre James,
Laub Gerhard,
Finn J Paul,
Hu Peng
Publication year - 2014
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.24842
Subject(s) - subtraction , image quality , contrast (vision) , image subtraction , image resolution , magnitude (astronomy) , iterative reconstruction , compressed sensing , digital subtraction angiography , temporal resolution , acceleration , noise (video) , computer science , magnetic resonance angiography , artificial intelligence , magnetic resonance imaging , nuclear medicine , computer vision , physics , angiography , mathematics , image (mathematics) , radiology , image processing , medicine , optics , arithmetic , classical mechanics , astronomy , binary image
Purpose We propose a compressed‐sensing (CS) technique based on magnitude image subtraction for high spatial and temporal resolution dynamic contrast‐enhanced MR angiography (CE‐MRA). Methods Our technique integrates the magnitude difference image into the CS reconstruction to promote subtraction sparsity. Fully sampled Cartesian 3D CE‐MRA datasets from 6 volunteers were retrospectively under‐sampled and three reconstruction strategies were evaluated: k‐space subtraction CS, independent CS, and magnitude subtraction CS. The techniques were compared in image quality (vessel delineation, image artifacts, and noise) and image reconstruction error. Our CS technique was further tested on seven volunteers using a prospectively under‐sampled CE‐MRA sequence. Results Compared with k‐space subtraction and independent CS, our magnitude subtraction CS provides significantly better vessel delineation and less noise at 4× acceleration, and significantly less reconstruction error at 4× and 8× ( P < 0.05 for all). On a 1–4 point image quality scale in vessel delineation, our technique scored 3.8 ± 0.4 at 4×, 2.8 ± 0.4 at 8×, and 2.3 ± 0.6 at 12× acceleration. Using our CS sequence at 12× acceleration, we were able to acquire dynamic CE‐MRA with higher spatial and temporal resolution than current clinical TWIST protocol while maintaining comparable image quality (2.8 ± 0.5 vs. 3.0 ± 0.4, P = NS). Conclusion Our technique is promising for dynamic CE‐MRA. Magn Reson Med 71:1771–1783, 2014. © 2013 Wiley Periodicals, Inc .