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In vivo 3D spatial/1D spectral imaging by spatiotemporal encoding: A new single‐shot experimental and processing approach
Author(s) -
Schmidt Rita,
Frydman Lucio
Publication year - 2013
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.24470
Subject(s) - encoding (memory) , computer science , imaging phantom , image resolution , artificial intelligence , spectral imaging , pattern recognition (psychology) , computer vision , biological system , physics , optics , biology
A novel method for acquiring and processing quality multislice spectroscopically resolved 2D images in a single shot is introduced and illustrated. By contrast to the majority of single‐scan spectroscopic imaging sequences developed so far, the method here discussed is not based on the acquisition of echo planar data in the k/t‐space, but rather on the use of recently proposed spatiotemporal encoding methods. These techniques provide a robust alternative to classical techniques, as they can scan two spatial plus one spectral dimension by oscillating a single imaging gradient. This work demonstrates that the use of extended spectral/spatial super‐resolution algorithms coupled to new experimental spatiotemporal encoding formulations based on swept inversions rather than on chirped excitations can lead to novel spatiotemporal encoding‐based tools for resolving complex multisliced 2D images according to the chemical shifts in subsecond experiments. A number of phantom‐based models were explored to clarify the relative merits of this technique and estimate its sensitivity performance. In vivo results of fat and water separation on abdominal imaging of mice at 7 T and on human breast imaging at 3 T are presented. Magn Reson Med 70:382–391, 2013. © 2012 Wiley Periodicals, Inc.