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Multiple 3D inversion recovery imaging for volume T 1 mapping of the heart
Author(s) -
Coniglio A.,
Di Renzi P.,
Vilches Freixas G.,
Della Longa G.,
Santarelli A.,
Capparella R.,
Nardiello B.,
Loiudice C.,
Bianchi S.,
D'Arienzo M.,
Begnozzi L.
Publication year - 2013
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.24248
Subject(s) - imaging phantom , nuclear medicine , computer science , partial volume , biomedical engineering , medicine
In this article, a three‐dimensional inversion recovery sequence was optimized with the aim of generating in vivo volume T 1 maps of the heart using a 1.5‐T MR system. Acquisitions were performed before and after gadolinium diethylenetriamine penta‐acetic acid (Gd‐DTPA) administration in one patient with hypertrophic cardiomyopathy and in two healthy volunteers. Data were acquired with a multishot fast field echo readout using both ECG and respiratory triggers. A dedicated phantom, composed of four solutions with different T 1 values, was positioned on the subjects' thoracic region to perform patient‐specific calibration. Pixel based T 1 maps were calculated with a custom Matlab ® code. Phantom measurements showed a good accuracy of the technique and in vivo T 1 estimation of liver, skeletal muscle, myocardium, and blood resulted in good agreement with values reported in the literature. Multiple three‐dimensional inversion recovery technique is a feasible and accurate method to perform T 1 volume mapping. Magn Reson Med, 2013. © 2012 Wiley Periodicals, Inc.