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Myocardial T 2 mapping with respiratory navigator and automatic nonrigid motion correction
Author(s) -
Giri Shivraman,
Shah Saurabh,
Xue Hui,
Chung YiuCho,
Pennell Michael L.,
Guehring Jens,
Zuehlsdorff Sven,
Raman Subha V.,
Simonetti Orlando P.
Publication year - 2012
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.24139
Subject(s) - computer vision , motion compensation , artificial intelligence , computer science , residual , standard deviation , motion (physics) , image registration , nuclear medicine , medicine , mathematics , algorithm , statistics , image (mathematics)
Abstract Quantitative T 2 mapping was recently shown to be superior to T 2 ‐weighted imaging in detecting T 2 changes across myocardium. Pixel‐wise T 2 mapping is sensitive to misregistration between the images used to generate the parameter map. In this study, utility of two motion‐compensation strategies—(i) navigator gating with prospective slice correction and (ii) nonrigid registration—was investigated for myocardial T 2 mapping in short axis and horizontal long axis views. Navigator gating provides respiratory motion compensation, whereas registration corrects for residual cardiac and respiratory motion between images; thus, the two strategies provided complementary functions. When these were combined, respiratory‐motion‐induced T 2 variability, as measured by both standard deviation and interquartile range, was comparable to that in breath‐hold T 2 maps. In normal subjects, this combined motion‐compensation strategy increased the percentage of myocardium with T 2 measured to be within normal range from 60.1% to 92.2% in short axis and 62.3% to 92.7% in horizontal long axis. The new motion‐compensated T 2 mapping technique, which combines navigator gating, prospective slice correction, and nonrigid registration to provide through‐plane and in‐plane motion correction, enables a method for fully automatic and robust free‐breathing T 2 mapping. Magn Reson Med, 2012. © 2012 Wiley Periodicals, Inc.