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Volume localized shift selective 13 C spectroscopy using pulsed rotating frame transfer sequences with windows (PRAWN)
Author(s) -
Banerjee Abhishek,
Chandrakumar N.
Publication year - 2011
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.22915
Subject(s) - polarization (electrochemistry) , spectroscopy , duty cycle , nuclear magnetic resonance , prawn , chemistry , volume (thermodynamics) , amplitude , materials science , optics , analytical chemistry (journal) , physics , atomic physics , chromatography , power (physics) , quantum mechanics , fishery , biology
Some novel techniques for volume localized, chemical shift selective 13 C spectroscopy are described in this work. These techniques are based on rotating frame J cross polarization and are reported for both direct and indirect modes of 13 C detection. The performance of two selective mixing sequences, viz., pulsed rotating frame transfer sequences with windows (PRAWN) and PRAWN‐π has been studied systematically with different liquid and gel phantoms. Two different front‐end modules are used for volume localization, viz., point resolved spectroscopy (PRESS) and localized distortionless enhancement by polarization transfer (LODEPT). It is shown experimentally that both the selective J cross polarization sequences can operate efficiently with very low radiofrequency duty cycle; further, they have considerable tolerance to Hartmann‐Hahn mismatch. A simple theoretical analysis is also presented to understand J cross‐polarization dynamics at low RF field amplitudes. Finally, the performance of LODEPT‐PRAWN‐π is demonstrated for the selective detection of saturated fat in pigeon egg in indirect detection mode. Magn Reson Med, 2011. © 2011 Wiley Periodicals, Inc.