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Three‐dimensional MR‐encephalography: Fast volumetric brain imaging using rosette trajectories
Author(s) -
Zahneisen Benjamin,
Grotz Thimo,
Lee Kuan J.,
Ohlendorf Sabine,
Reisert Marco,
Zaitsev Maxim,
Hennig Jürgen
Publication year - 2011
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.22711
Subject(s) - blood oxygenation , computer science , temporal resolution , image resolution , sampling (signal processing) , block (permutation group theory) , artificial intelligence , computer vision , functional magnetic resonance imaging , physics , optics , neuroscience , mathematics , geometry , biology , filter (signal processing)
MR‐Encephalography (MREG) is a technique that allows real time observation of functional changes in the brain that appears within 100 msec. The high sampling rate is achieved at the cost of some spatial resolution. The article describes a novel imaging method for fast three‐dimensional‐MR‐encephalography whole brain coverage based on rosette trajectories and the use of multiple small receiver coils. The technique allows the observation of changes in brain physiology at very high temporal resolution. A highly undersampled three‐dimensional rosette trajectory is chosen, to perform single shot acquisition of k ‐space data within 23 msec. By using a 32‐channel head coil array and regularized nonuniform Fourier transformation reconstruction, the spatial resolution is sufficient to detect even subtle centers of activation (e.g. human MT+). The method was applied to visual block design paradigms and compared with echo planar imaging‐based functional MRI. As a proof‐of‐principle of the method's ability to detect local differences in the hemodynamic response functions, the analyzed MR‐encephalography data revealed a spatially dependent delay of the arrival of the blood oxygenation level dependent response within the visual cortex. Magn Reson Med, 2011. © 2011 Wiley‐Liss, Inc.