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Assessment of MR compatibility of a PET insert developed for simultaneous multiparametric PET/MR imaging on an animal system operating at 7 T
Author(s) -
Wehrl Hans F.,
Judenhofer Martin S.,
Thielscher Axel,
Martirosian Petros,
Schick Fritz,
Pichler Bernd J.
Publication year - 2011
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.22591
Subject(s) - positron emission tomography , positron emission , positron , tomography , brain positron emission tomography , homogeneity (statistics) , preclinical imaging , image quality , magnetic resonance imaging , nuclear medicine , insert (composites) , materials science , nuclear magnetic resonance , physics , medical physics , computer science , medicine , optics , radiology , artificial intelligence , nuclear physics , in vivo , microbiology and biotechnology , composite material , machine learning , biology , image (mathematics) , electron
The combination of positron emission tomography and MR in one system is currently emerging and opens up new domains in the functional examinations of living systems. This article reports on relevant influences of a positron emission tomography insert on MR imaging. The basic conditions of main magnetic field and RF field homogeneity were measured as well as image quality and signal‐to‐noise ratio when applying the usual MR sequence types including echo‐planar techniques. Moreover, the influence of the positron emission tomography insert on the RF noise level and on RF interferences was measured by comparing results achieved with and without the positron emission tomography insert. The temporal stability of EPI imaging with and without the positron emission tomography insert was assessed. Small but significant decreases in the signal‐to‐noise ratio were revealed when the positron emission tomography insert was present, whereas B 0 and B 1 homogeneity as well as RF noise level were not adversely affected. A higher signal intensity drift was found for EPI imaging studies; however, this can be compensated by post processing. In summary, this study shows that positron emission tomography inserts can be designed for and used within an MR system practically, without substantially affecting the MR image quality. Magn Reson Med, 2010. © 2010 Wiley‐Liss, Inc.