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Compressed sensing in hyperpolarized 3 He Lung MRI
Author(s) -
Ajraoui Salma,
Lee Kuan J.,
Deppe Martin H.,
Parnell Steven R.,
ParraRobles Juan,
Wild Jim M.
Publication year - 2010
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.22302
Subject(s) - compressed sensing , nuclear medicine , wavelet , signal to noise ratio (imaging) , computer science , image resolution , nuclear magnetic resonance , artificial intelligence , physics , mathematics , medicine , optics
Abstract In this work, the application of compressed sensing techniques to the acquisition and reconstruction of hyperpolarized 3 He lung MR images was investigated. The sparsity of 3 He lung images in the wavelet domain was investigated through simulations based on fully sampled Cartesian two‐dimensional and three‐dimensional 3 He lung ventilation images, and the k ‐spaces of 2D and 3D images were undersampled randomly and reconstructed by minimizing the L1 norm. The simulation results show that temporal resolution can be readily improved by a factor of 2 for two‐dimensional and 4 to 5 for three‐dimensional ventilation imaging with 3 He with the levels of signal to noise ratio (SNR) (∼19) typically obtained. The feasibility of producing accurate functional apparent diffusion coefficient (ADC) maps from undersampled data acquired with fewer radiofrequency pulses was also demonstrated, with the preservation of quantitative information (mean ADC cs ∼ mean ADC full ∼ 0.16 cm 2 sec −1 ). Prospective acquisition of 2‐fold undersampled two‐dimensional 3 He images with a compressed sensing k ‐space pattern was then demonstrated in a healthy volunteer, and the results were compared to the equivalent fully sampled images (SNR cs = 34, SNR full = 19). Magn Reson Med 63:1059–1069, 2010. © 2010 Wiley‐Liss, Inc.