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MRI and localized proton spectroscopy in human leg muscle at 7 tesla using longitudinal traveling waves
Author(s) -
Webb Andrew G.,
Collins Christopher M.,
Versluis Maarten J.,
Kan Hermien E.,
Smith Nadine B.
Publication year - 2010
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.22262
Subject(s) - electromagnetic coil , nuclear magnetic resonance , signal (programming language) , physics , noise (video) , spectroscopy , flexibility (engineering) , signal to noise ratio (imaging) , acoustics , spectral line , proton , optics , computer science , mathematics , artificial intelligence , nuclear physics , statistics , quantum mechanics , astronomy , image (mathematics) , programming language
Using a small resonant loop to produce a longitudinal traveling wave on a human 7‐T system allows MR to be performed over the entire volume of the human leg. We have used this capability to perform localized proton MR spectroscopy of the lipid composition of muscle in volunteers with a coil placed ∼30 cm away from the region of interest. Spectra with a reasonable signal‐to‐noise ratio can be acquired in a clinically relevant data acquisition time of less than 5 min using the loop in transmit/receive mode, maintaining the full flexibility to acquire spectra from any part of the calf and/or thigh. If a local receive coil is used in combination with the remote transmit coil, then the signal‐to‐noise improves significantly, as expected. Magn Reson Med, 2010. © 2010 Wiley‐Liss, Inc.