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Non‐contrast‐enhanced four‐dimensional (4D) intracranial MR angiography: A feasibility study
Author(s) -
Bi Xiaoming,
Weale Peter,
Schmitt Peter,
Zuehlsdorff Sven,
Jerecic Renate
Publication year - 2010
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.22220
Subject(s) - contrast (vision) , temporal resolution , image resolution , magnetic resonance angiography , magnetic resonance imaging , angiography , nuclear magnetic resonance , resolution (logic) , computer science , radiology , nuclear medicine , optics , physics , medicine , artificial intelligence
T 1 ‐shortening contrast agents have been widely used in time‐resolved magnetic resonance angiography. To match imaging data acquisition with the short time period of the first pass of contrast agent, temporal resolution and/or spatial resolution have to be compromised in many cases. In this study, a novel non‐contrast‐enhanced technique was developed for time‐resolved magnetic resonance angiography. Alternating magnetization preparation was applied in two consecutive acquisitions of each measurement to eliminate the need for contrast media. Without the constraint of contrast media kinetics, temporal resolution is drastically improved from the order of a second as in conventional contrast‐enhanced approach to tens of milliseconds (50.9 msec) in this study, without compromising spatial resolution. Initial results from volunteer studies demonstrate the feasibility of this method to depict anatomic structure and dynamic filling of main vessels in the head. Magn Reson Med 63:835–841, 2010. © 2010 Wiley‐Liss, Inc.