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Myocardial 3D strain calculation by combining cine displacement encoding with stimulated echoes (DENSE) and cine strain encoding (SENC) imaging
Author(s) -
Hess Aaron T.,
Zhong Xiaodong,
Spottiswoode Bruce S.,
Epstein Frederick H.,
Meintjes Ernesta M.
Publication year - 2009
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.21984
Subject(s) - strain (injury) , displacement (psychology) , infinitesimal strain theory , kinematics , encoding (memory) , deformation (meteorology) , orientation (vector space) , physics , computer science , anatomy , mathematics , geometry , artificial intelligence , medicine , finite element method , psychology , classical mechanics , psychotherapist , meteorology , thermodynamics
Three‐dimensional (3D) strain maps of the myocardium provide a coordinate‐system–independent quantification of myocardial deformation and kinematics. We combine two MRI techniques, displacement encoding with stimulated echoes (DENSE) and strain encoding (SENC), to fully formulate a 3D strain map in a single slice of myocardium. The method utilizes 2D DENSE in‐plane displacement measurements in two adjacent slices in conjunction with a single SENC through‐plane strain measure to calculate the 3D strain tensor. Six volunteers were imaged and the technique demonstrated 3D strain measures in all volunteers that are consistent with those reported in the literature from 3D tagging. The mean peak strain (± standard deviation [SD]) for six healthy volunteers for the first, second, and third principal strains are 0.42 ±0.11, –0.10 ±0.03, and –0.21 ±0.02, respectively. These results show that this technique is capable of reliably quantifying 3D cardiac strain. Magn Reson Med, 2009. © 2009 Wiley‐Liss, Inc.