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Regional pulmonary blood flow: Comparison of dynamic contrast‐enhanced MR perfusion and phase‐contrast MR
Author(s) -
van Amerom Joshua F.P.,
Vidarsson Logi,
Wu Shengping,
Tessler Rogerio,
Yoo ShiJoon,
Belik Jaques,
Macgowan Christopher K.
Publication year - 2009
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.21940
Subject(s) - dynamic contrast , blood flow , perfusion , medicine , lung , contrast (vision) , nuclear medicine , magnetic resonance imaging , dynamic contrast enhanced mri , radiology , computer science , artificial intelligence
Regional pulmonary blood flow can be assessed using both dynamic contrast‐enhanced (DCE) MR and phase‐contrast (PC) MR. These methods provide somewhat complementary information: DCE MR can assess flow over the entire lung while PC MR can detect rapid changes in flow to a targeted region. Although both methods are considered accurate, one may be more feasible than the other depending on pathology, patient condition, and availability of an intravenous route. The objective of this study was to establish a consensus between the two methods by comparing paired DCE MR and PC MR measurements of relative blood flow in Yorkshire piglets ( N = 5, age = 7 days, weight = 3.3 ± 0.6 kg) under various physiological states including regional lung collapse. A strong correlation (R 2 = 0.71, P < 0.01) was observed between the methods. In conclusion, DCE MR and PC MR provide a consistent measure of changes in regional pulmonary blood flow. Magn Reson Med, 2009. © 2009 Wiley‐Liss, Inc.