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Effects of echo time on diffusion quantification of brain white matter at 1.5T and 3.0T
Author(s) -
Qin Wen,
Shui Yu Chun,
Zhang Fan,
Du Xiang Ying,
Jiang Heng,
Xia Yan Yu,
Cheng Li Kun
Publication year - 2009
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.21920
Subject(s) - fractional anisotropy , diffusion mri , white matter , nuclear magnetic resonance , lambda , nuclear medicine , physics , medicine , magnetic resonance imaging , optics , radiology
The aim was to investigate the effects of echo time (TE) on diffusion quantification of brain white matter. Seven rhesus monkeys (all males; age, 4–6 years; weight, 5–7 kg) underwent diffusion tensor imaging (DTI) with a series of TEs in 1.5T and 3.0T MR scanners. The mean diffusivity (MD), fractional anisotropy (FA), primary (λ 1 ), and transverse eigenvalues (λ 23 ) were measured in a region of interest at the bilateral internal capsule. Pearson correlation showed that the FA and λ 1 increased and λ 23 decreased with TE both at 1.5T and 3.0T except for the MD. Repeated measurement analysis of variance (ANOVA) also showed significantly higher FA and lower MD and λ 23 at 3.0T than those at 1.5T ( P < 0.01), but no statistical differences were found in λ 1 between these two field strengths ( P = 0.709). These findings implied that TE and field strength might influence diffusion quantification in brain white matter. Magn Reson Med, 2009. © 2009 Wiley‐Liss, Inc.