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Fast high‐resolution T 1 mapping using inversion‐recovery look‐locker echo‐planar imaging at steady state: Optimization for accuracy and reliability
Author(s) -
Shin Wanyong,
Gu Hong,
Yang Yihong
Publication year - 2009
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.21836
Subject(s) - echo planar imaging , planar , echo (communications protocol) , high resolution , inversion (geology) , nuclear magnetic resonance , superresolution , resolution (logic) , reliability (semiconductor) , computer science , physics , magnetic resonance imaging , remote sensing , geology , artificial intelligence , image (mathematics) , radiology , medicine , paleontology , power (physics) , computer graphics (images) , structural basin , quantum mechanics , computer network
A fast T 1 measurement sequence using inversion recovery Look‐Locker echo‐planar imaging at steady state (IR LL‐EPI SS) is presented. Delay time for a full magnetization recovery is not required in the sequence, saving acquisition time significantly for high‐resolution T 1 mapping. Imaging parameters of the IR LL‐EPI SS sequence were optimized to minimize the bias from the excitation pulses imperfection and to maximize the accuracy and reliability of T 1 measurements, which are critical for its applications. Compared with the conventional inversion recovery Look‐Locker echo‐planar imaging (IR LL‐EPI) sequence, IR LL‐EPI SS method preserves similar accuracy and reliability, while saving 20% in acquisition time. Optimized IR LL‐EPI SS provided quantitative T 1 mapping with 1 × 1 × 4 mm 3 resolution and whole‐brain coverage (28 slices) in approximately 4 min. Magn Reson Med, 2009. © 2009 Wiley‐Liss, Inc.
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