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Minimizing acquisition time of arterial spin labeling at 3T
Author(s) -
FernándezSeara María A.,
Edlow Brian L.,
Hoang Angela,
Wang Jiongjiong,
Feinberg David A.,
Detre John A.
Publication year - 2008
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.21633
Subject(s) - arterial spin labeling , perfusion , stroke (engine) , lesion , nuclear medicine , perfusion scanning , nuclear magnetic resonance , coefficient of variation , site directed spin labeling , medicine , biomedical engineering , cardiology , chemistry , physics , pathology , chromatography , thermodynamics , electron paramagnetic resonance
An improved arterial spin labeling (ASL) perfusion technique that combines pseudo‐continuous labeling and a T 2 *‐insensitive sequence (GRASE) with background suppression was used to acquire perfusion maps in normal volunteers and stroke patients. It is shown that perfusion measurements obtained in less than 1 min of scan time are reproducible, with a coefficient of variation of 7%. The perfusion maps generated from these data can be used to characterize the stroke lesion. Magn Reson Med 59:1467–1471, 2008. © 2008 Wiley‐Liss, Inc.