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Circumferential strain in the wall of the common carotid artery: Comparing displacement‐encoded and cine MRI in volunteers
Author(s) -
Lin Alexander P.,
Bennett Eric,
Wisk Lauren E.,
Gharib Morteza,
Fraser Scott E.,
Wen Han
Publication year - 2008
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.21621
Subject(s) - steady state free precession imaging , pulsatile flow , displacement (psychology) , lumen (anatomy) , carotid arteries , common carotid artery , circumference , artery , strain (injury) , nuclear magnetic resonance , anatomy , medicine , physics , materials science , magnetic resonance imaging , radiology , cardiology , mathematics , geometry , psychology , psychotherapist
Abstract The walls of conduit arteries undergo cyclic stretching from the periodic fluctuation of arterial pressure. Atherosclerotic lesions have been shown to localize to regions of excessive stretching of the arterial wall. We employed a displacement encoding with stimulated echoes (DENSE) sequence to image the motion of the common carotid artery wall and map the two‐dimensional (2D) circumferential strain. The sequence utilizes a fully‐balanced steady‐state free‐precession (SSFP) readout with 0.60 mm in‐plane resolution. Preliminary results in volunteers at 1.5T ( N = 4) and 3.0T ( N = 17) are compared to measurements of the lumen circumference from cine images. The agreement between the two independent measurements at both field strengths ( P ≤ 0.001) supports the use of DENSE as a means to map the pulsatile strain in the carotid artery wall. Magn Reson Med 60:8–13, 2008. © 2008 Wiley‐Liss, Inc.