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Influence of the k ‐space trajectory on the dynamic T 1 ‐weighted signal in quantitative first‐pass cardiac perfusion MRI at 3T
Author(s) -
Kim Daniel
Publication year - 2008
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.21344
Subject(s) - trajectory , signal (programming language) , space (punctuation) , mathematics , perfusion , first pass , function (biology) , mathematical analysis , algorithm , nuclear magnetic resonance , nuclear medicine , physics , computer science , medicine , cardiology , arithmetic , astronomy , evolutionary biology , biology , programming language , operating system
The dynamic T 1 ‐weighted signal in first‐pass myocardial perfusion MRI can vary as a function of k ‐space trajectory. The purpose of this study, therefore, was to compare the relative T 1 ‐weighted signal produced by the linear, centric, and reverse centric k ‐space trajectories at 3T. The centric k ‐space trajectory yielded higher arterial input function (AIF) than the linear and reverse centric k ‐space trajectories (6.21 ± 0.84 vs. 4.75 ± 0.75 vs. 4.39 ± 0.85 mM, respectively; N = 9; P < 0.01), and the reverse centric k ‐space trajectory yielded higher myocardial signal contrast (as a fraction of equilibrium magnetization) than the linear and centric k ‐space trajectories (0.17 ± 0.02 vs. 0.12 ± 0.02 vs. 0.05 ± 0.01, respectively; N = 9; P < 0.001). Compared to the linear k ‐space trajectory, the centric k ‐space trajectory is relatively optimal for the quantification of AIF, whereas the reverse centric k ‐space trajectory is relatively optimal for high contrast of myocardial wall enhancement. Magn Reson Med, 2007. © 2007 Wiley‐Liss, Inc.