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Improved reproducibility of right ventricular volumes and function estimation from cardiac magnetic resonance images using level‐set models
Author(s) -
Catalano Oronzo,
Corsi Cristiana,
Antonaci Serena,
Moro Guido,
Mussida Maria,
Frascaroli Mauro,
Baldi Maurizia,
Caiani Enrico,
Lamberti Claudio,
Cobelli Franco
Publication year - 2007
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.21157
Subject(s) - reproducibility , limits of agreement , coefficient of variation , magnetic resonance imaging , nuclear medicine , ejection fraction , cardiac magnetic resonance imaging , ventricular volume , stroke volume , cardiac magnetic resonance , volume (thermodynamics) , bland–altman plot , mathematics , nuclear magnetic resonance , medicine , cardiology , radiology , physics , statistics , heart failure , quantum mechanics
This study aims to assess whether an alternative method, that is based on volumetric surface detection (VoSD) without tracing and is totally free of geometric assumptions, can improve the reproducibility of right ventricular (RV) volume quantification from cardiac magnetic resonance (CMR) images, in comparison with a conventional disk‐area technique. In a sample of 23 patients, with wide variability of RV end‐diastolic volume (EDV: 47–131 ml), end‐systolic volume (ESV: 20–76 ml), and ejection fraction (EF: 29–73%), using the standard method (Argus, Siemens) as the reference, the VoSD method showed good agreement for EDV, ESV, and EF estimations (correlation coefficient: 0.91, 0.94, and 0.94; Bland‐Altman biases: 1 ml, 1 ml, and 0%; limits of agreement: ±16 ml, ±11 ml, and ±11%, respectively). An analysis of the reproducibility of the two methods showed lower intraobserver variability for the VoSD method than for the conventional method, as evidenced by the coefficient of variability (CoV) values (2–6% vs. 8–15%; P < 0.05). In addition, the VoSD method showed improved interobserver reproducibility (7–10% vs. 8–15%), but the difference was statistically significant only for EF estimation variability (8 vs. 15%, P < 0.05). In conclusion, the newly developed VoSD technique allows accurate measurements of RV volumes and function, and appears to be more reproducible than the conventional methodology. Magn Reson Med 57:600–605, 2007. © 2007 Wiley‐Liss, Inc.