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Rapid MR elastography using selective excitations
Author(s) -
Glaser Kevin J.,
Felmlee Joel P.,
Ehman Richard L.
Publication year - 2006
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.20913
Subject(s) - elastography , imaging phantom , materials science , magnetic resonance elastography , beam (structure) , nuclear magnetic resonance , gradient echo , biomedical engineering , optics , physics , magnetic resonance imaging , acoustics , radiology , ultrasound , medicine
Rapid MR elastography (MRE) techniques using spatially‐selective excitations to reduce acquisition times to a few seconds or less were devised and tested. The techniques included reduced field of view (rFOV) MRE and 1D MRE (beam MRE) using 2D spatially selective RF excitations for gradient‐echo (GRE) applications and intersecting 90° and 180° slice‐selective excitations for spin‐echo (SE) applications. It was shown that scan times could be reduced by a factor of 8 using rFOV MRE, and by 64 using beam MRE, while still obtaining stiffness estimates comparable to full‐FOV MRE. Results were shown in gel phantom experiments as well as in the case of a preserved postmortem breast tissue specimen with a stiff lesion. These methods can be used to more rapidly interrogate regions of interest (ROIs) in tissue to quickly obtain information about the viscoelastic properties of that tissue. Magn Reson Med, 2006. © 2006 Wiley‐Liss, Inc.