Nuclear magnetic resonance parameters for monitoring coagulation of liver tissue | Zendy

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Nuclear magnetic resonance parameters for monitoring coagulation of liver tissue

Author(s) -

Carasso Dina,

Eliav Uzi,

Navon Gil

Publication year - 2005

Publication title -

magnetic resonance in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.696

H-Index - 225

eISSN - 1522-2594

pISSN - 0740-3194

DOI - 10.1002/mrm.20693

Subject(s) - nuclear magnetic resonance , coagulation , relaxation (psychology) , chemistry , magnetization , magnetization transfer , liver tissue , proton , magnetic resonance imaging , biophysics , physics , magnetic field , biology , nuclear physics , medicine , radiology , quantum mechanics

A new NMR parameter is suggested as a sensitive tool for monitoring thermal coagulation of liver tissue. That parameter is the proton magnetization exchange time (τ MEX ) between water and the proteins. τ MEX was very sensitive to coagulation and insensitive to temperature, therefore representing only damage to the tissue, independent of effects caused by temperature fluctuations. The measurement of τ MEX by two different methods revealed the existence of two or more groups of proteins, characterized by their different transverse relaxation time, and τ MEX . Magn Reson Med, 2005. © 2005 Wiley‐Liss, Inc.

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