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In vivo prostate magnetic resonance spectroscopic imaging using two‐dimensional J‐resolved PRESS at 3 T
Author(s) -
Kim Donghyun,
Margolis Daniel,
Xing Lei,
Daniel Bruce,
Spielman Daniel
Publication year - 2005
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.20452
Subject(s) - nuclear magnetic resonance , magnetic resonance spectroscopic imaging , magnetic resonance imaging , voxel , in vivo , metabolite , imaging phantom , in vivo magnetic resonance spectroscopy , nuclear magnetic resonance spectroscopy , chemistry , spiral (railway) , spectroscopy , physics , optics , medicine , radiology , mathematics , biology , mathematical analysis , biochemistry , microbiology and biotechnology , quantum mechanics
In vivo magnetic resonance spectroscopic imaging of the prostate using single‐voxel and multivoxel two‐dimensional (2D) J ‐resolved sequences is investigated at a main magnetic field strength of 3 T. Citrate, an important metabolite often used to aid the detection of prostate cancer in magnetic resonance spectroscopic exams, can be reliably detected along with the other metabolites using this method. We show simulations and measurements of the citrate metabolite using 2D J ‐resolved spectroscopy to characterize the spectral pattern. Furthermore, using spiral readout gradients, the single‐voxel 2D J ‐resolved method is extended to provide the spatial distribution information as well all within a reasonable scan time (17 min). Phantom and in vivo data are presented to illustrate the multivoxel 2D J ‐resolved spiral chemical shift imaging sequence. Magn Reson Med 53:1177–1182, 2005. © 2005 Wiley‐Liss, Inc.