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Correction for partial volume errors in MR heart perfusion imaging
Author(s) -
Köstler Herbert,
Ritter Christian,
ReissZimmermann Martin,
Beer Meinrad,
Hahn Dietbert,
Sandstede Jörn
Publication year - 2004
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.20015
Subject(s) - perfusion , signal (programming language) , intensity (physics) , partial volume , contamination , volume (thermodynamics) , biomedical engineering , nuclear medicine , nuclear magnetic resonance , computer science , medicine , radiology , physics , optics , ecology , quantum mechanics , biology , programming language
Myocardial MR first‐pass perfusion time courses are contaminated by signals from the ventricles (spillover) as a consequence of partial volume effects and motion. An early increase in the signal intensity from the myocardium is an indicator of contamination. This contamination leads to under‐ or overestimation of perfusion, depending on the amount of contamination. In this work a simple method for contamination correction is proposed: curves proportional to the signal intensity time courses in the ventricles are subtracted from the signal intensity time courses in the myocardium to minimize the variance of signal before the arrival of the contrast medium in the myocardium. The proposed correction is easy to apply, removes the contamination, and leads to more precise perfusion values. Magn Reson Med 51:848–852, 2004. © 2004 Wiley‐Liss, Inc.