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3D DT‐MRI using a reduced‐FOV approach and saturation pulses
Author(s) -
Wang JiunJie,
Deichmann Ralf,
Turner Robert,
Ordidge Roger
Publication year - 2004
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.20012
Subject(s) - ghosting , diffusion mri , image quality , image resolution , computer science , single shot , computer vision , artificial intelligence , physics , nuclear magnetic resonance , magnetic resonance imaging , optics , image (mathematics) , medicine , radiology
Diffusion tensor imaging (DTI) can provide vital insights into brain connectivity, and may become an important tool for the diagnosis and treatment of neurological disease. However, DTI's intrinsic low signal‐to‐noise ratio (SNR) and vulnerability to ghosting artifacts can result in poor image quality with low spatial resolution, which limits its clinical applications. In this study, a new double‐shot EPI sequence (half‐FOV EPI) with high spatial resolution was developed. This method enables DT measurements to be obtained with high isotropic spatial resolution and whole‐brain coverage. To avoid ghosting artifacts, the data are combined in image space rather than in k ‐space. Magn Reson Med 51:853–857, 2004. © 2004 Wiley‐Liss, Inc.