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A systematic study of the lactate lineshape in PRESS‐localized proton spectroscopy
Author(s) -
Marshall Ian,
Wild James
Publication year - 1998
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910400111
Subject(s) - spectroscopy , nuclear magnetic resonance , polarization (electrochemistry) , echo time , pulse sequence , nuclear magnetic resonance spectroscopy , atomic physics , computational physics , chemistry , physics , materials science , quantum mechanics , magnetic resonance imaging , medicine , radiology
J ‐coupled resonances such as lactate exhibit complex behavior in PRESS‐localized spectroscopy. Polarization transfer effects due to nonideal slice profiles can lead to substantial errors in quantification unless recognized. In this work, it is shown how these effects can be predicted in a systematic way given the sequence timing and the RF pulse envelopes. Experimental results are presented to highlight the problems of working at the popular echo time of 2/ J .