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An MR‐based technique for quantifying the deformation of articular cartilage during mechanical loading in an intact cadaver joint
Author(s) -
Herberhold Christoph,
Stammberger Tobias,
Faber Sonja,
Putz Reinhard,
Englmeier KarlHans,
Reiser Maximilian,
Eckstein Felix
Publication year - 1998
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910390522
Subject(s) - cadaver , biomedical engineering , cartilage , articular cartilage , joint (building) , deformation (meteorology) , materials science , compression (physics) , scanner , anatomy , osteoarthritis , medicine , composite material , computer science , structural engineering , pathology , artificial intelligence , alternative medicine , engineering
The objective of this study was to develop an MR‐based technique for quantifying the deformation of articular cartilage during mechanical loading in an intact cadaver joint at high spatial and temporal resolution. A nonmetallic pressure device was constructed for applying loads of >1000 N to a femoro‐patellar articulation within an extremity coil of a clinical 1.5 T MRI scanner. Digital image processing methods were used to determine the location‐ and time‐dependent cartilage deformation in consecutive 2D fat‐suppressed FLASH images. Additionally, three‐dimensional reconstruction of the cartilage was performed from 3D fat‐suppressed FLASH image data. During the first 10 min of static compression, thickness changes between 10 and 30% were observed. Thickness changes greater than 50% and volume changes of 20% were recorded after 3 h. The technique permits analysis of the load and time‐dependent mechanical behavior of articular cartilage in its natural environment.