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Imaging asynchronous mechanical activation of the paced heart with tagged MRI
Author(s) -
McVeigh Elliot R.,
Prinzen Frits W.,
Wyman Bradley T.,
Tsitlik Joshua E.,
Halperin Henry R.,
Hunter William C.
Publication year - 1998
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910390402
Subject(s) - ventricle , systole , apex (geometry) , magnetic resonance imaging , left ventricles , biomedical engineering , medicine , cardiology , anatomy , radiology , diastole , blood pressure
A method for imaging the rapid temporal‐spatial evolution of myocardial deformations in the paced heart is proposed. High time resolution‐tagged MR images were obtained after stimulation of the myocardium with an MR‐compatible pacing system. The images were analyzed to reconstruct dynamic models of local 3D strains over the entire left ventricle during systole. Normal canine hearts were studied in vivo with pacing sites on the right atrium, left ventricular free wall and right ventricular apex. This method clearly resolved local variations in myocardial contraction patterns caused by ventricular pacing. Potential applications are noninvasive determination of electrical conduction abnormalities and the evaluation of new pacing therapies.