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Functional MRI using steady‐state arterial water labeling
Author(s) -
Talagala S. Lalith,
Noll Douglas C.
Publication year - 1998
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910390203
Subject(s) - nuclear magnetic resonance , steady state (chemistry) , chemistry , physics
Flow‐sensitive functional MRI (fMRI) was performed using steady‐state arterial water labeling (SS‐AWL). Arterial water labeling was accomplished by flow induced adiabatic fast passage. The signal intensity of the visual cortex in arterial water labeled images decreased by ˜1.4% during visual stimulation of the brain. Acquisition of arterial water unlabeled and labeled images allows measurement of relative cerebral blood flow increase during brain activation. During visual stimulation, cerebral blood flow in the visual cortex increased by 17 to 35% as measured by SS‐AWL. Quantitation of brain activation in terms of a physiological parameter using SS‐AWL will facilitate comparative fMRI studies under different conditions.