Premium
Observation of a 1 H double quantum filtered signal of water in biological tissues
Author(s) -
Tsoref Liat,
Shinar Hadassah,
Navon Gil
Publication year - 1998
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910390104
Subject(s) - tendon , nuclear magnetic resonance , macromolecule , chemistry , sciatic nerve , nuclear magnetic resonance spectroscopy , dipole , residual dipolar coupling , biophysics , materials science , anatomy , physics , biology , biochemistry , organic chemistry
The observation of a 1 H double quantum filtered (DQF) NMR signal of water in bovine sciatic nerve, bovine articular cartilage, rat tail tendon, and rat brain is reported. The origin of this signal in rat tail tendon was found to be a result of residual dipolar interaction between water protons and macromolecular protons. The dependence of the width of the 1 H DQF spectra on the orientation indicated that in rat tail tendon the effective director of the residual dipolar interaction is parallel to the collagen fibers. 1 H DQF NMR may be applied in imaging where the contrast obtained is related to the degree of order in the tissue.