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Multi‐gradient echo with susceptibility inhomogeneity compensation (MGESIC): Demonstration of f MRI in the olfactory cortex at 3.0 T
Author(s) -
Yang Qing X.,
Dardzinski Bernard J.,
Li Shizhe,
Eslinger Paul J.,
Smith Michael B.
Publication year - 1997
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910370304
Subject(s) - quantitative susceptibility mapping , sensitivity (control systems) , echo (communications protocol) , gradient echo , signal (programming language) , nuclear magnetic resonance , magnetic resonance imaging , computer science , magnetic susceptibility , cortex (anatomy) , compensation (psychology) , neuroscience , physics , psychology , medicine , radiology , computer network , electronic engineering , psychoanalysis , engineering , programming language , quantum mechanics
Short image acquisition times and sensitivity to magnetic susceptibility favor the use of gradient echo imaging methods in functional MRI ( f MRI). However, magnetic susceptibility effects attributed to air‐tissue interfaces also lead to severe signal loss in images of the large inferior frontal and lateral temporal cortices of the human brain, which renders these regions inaccessible to f MRI. The signal loss is caused by the local field gradients in the slice selection direction. A multigradient echo with magnetic susceptibility inhomogeneity compensation method (MGESIC) is proposed to overcome this problem. The MGESIC method effectively corrects the susceptibility artifacts and maintains the advantages of gradient echo methods to both BOLD sensitivity and fast image acquisition. The effectiveness of the MGESIC method is demonstrated by f MRI experimental results within the olfactory cortex.