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Fast 3D functional magnetic resonance imaging at 1.5 T with spiral acquisition
Author(s) -
Yang Yihong,
Glover Gary H.,
van Gelderen Peter,
Mattay Venkata S.,
Santha Attanagoda K. S.,
Sexton Roy H.,
Ramsey Nick F.,
Moonen Chrit T. W.,
Weinberger Daniel R.,
Frank Joseph A.,
Duyn Jeff H.
Publication year - 1996
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910360418
Subject(s) - magnetic resonance imaging , nuclear magnetic resonance , functional magnetic resonance imaging , spiral (railway) , magnetic resonance spectroscopic imaging , functional imaging , physics , medicine , radiology , mathematics , mathematical analysis
A new method to perform rapid 3D fMRI in human brain is introduced and evaluated in normal subjects, on a standard clinical scanner at 1.5 Tesla. The method combines a highly stable gradient echo technique with a spiral scan method, to detect brain activation related changes in blood oxygenation with high sensitivity. A motor activation paradigm with a duration of less than 5 min, performed on 10 subjects, consistently showed significant changes in signal intensity in the area of the motor cortex. In all subjects, these changes survived high statistical thresholds.