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A method for generating magnetic resonance microimaging T 2 maps with low sensitivity to diffusion
Author(s) -
Mlynárik Vladimír,
Degrassi Anna,
Toffanin Renato,
Jarh Orest,
Vittur Franco
Publication year - 1996
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910350321
Subject(s) - pulse sequence , nuclear magnetic resonance , relaxation (psychology) , diffusion , sensitivity (control systems) , spin echo , magnetic resonance imaging , t2 relaxation , sequence (biology) , chemistry , resonance (particle physics) , analytical chemistry (journal) , materials science , physics , atomic physics , thermodynamics , chromatography , medicine , psychology , social psychology , biochemistry , radiology , electronic engineering , engineering
Generating T 2 maps in magnetic resonance microimaging is often complicated by the self‐diffusion of water molecules. A modification of the standard spin‐echo pulse sequence is proposed which minimizes this effect. Experiments with doped water confirmed that the T 2 values obtained with the modified sequence were equal within the experimental error to the value obtained by the spectroscopic Carr‐Purcell‐Meiboom‐Gill method. The applicability of the technique is demonstrated by generating T 2 maps of porcine articular cartilage. Key words: MR microimaging; relaxation; diffusion; cartilage.