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High resolution solid‐state 29 si nmr spectroscopy of silicone gels used to fill breast prostheses
Author(s) -
Dorne Laurence,
Alikacem Nadir,
Guidoin Robert,
Auger Michèle
Publication year - 1995
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910340411
Subject(s) - silicone , nuclear magnetic resonance spectroscopy , materials science , spectroscopy , nuclear magnetic resonance , high resolution , solid state nuclear magnetic resonance , chemistry , analytical chemistry (journal) , composite material , chromatography , physics , remote sensing , quantum mechanics , geology
We have used 29 Si solid‐state nuclear magnetic resonance (NMR) spectroscopy to study the chemical structure of the silicone gels in virgin and explanted breast prostheses. Despite evidences of alteration in the morphological appearance of the silicone gel inside the breast prosthesis, our results do not reveal changes in the chemical nature and structure of the silicone gels after implantation. In addition to the main 29 Si resonance peak at −22.26 ppm that corresponds to the resonance frequency of the D repeat unit of the polysiloxane chains, the high sensitivity of our NMR technique allows the detection of very low concentrations of silicone compounds. Within our experimental detection limit of 0.2%, no signal between −90 ppm and −150 ppm are observed. This indicates that no silica products are present inside the gel of the prostheses. Furthermore, our 29 Si NMR spectra indicate differences in the chemical compositions of the silicone gels from different manufacturers.