1 H mrs of human brain abscesses  in vivo  and  in vitro | Zendy

Rémy Chantal | Zendy; Grand Sylvie | Zendy; Laï Ernest Sam | Zendy; Belle ValéRie | Zendy; Hoffmann Dominique | Zendy; Berger FrançOis | Zendy; Estève FrançOis | Zendy; Ziegler Anne | Zendy; Bas JeanFrsançOis Le | Zendy; Benabid Alim L. | Zendy; Décorps Michel | Zendy; Segebarth Christoph M. | Zendy

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1 H mrs of human brain abscesses in vivo and in vitro

Author(s) -

Rémy Chantal,

Grand Sylvie,

Laï Ernest Sam,

Belle ValéRie,

Hoffmann Dominique,

Berger FrançOis,

Estève FrançOis,

Ziegler Anne,

Bas JeanFrsançOis Le,

Benabid Alim L.,

Décorps Michel,

Segebarth Christoph M.

Publication year - 1995

Publication title -

magnetic resonance in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.696

H-Index - 225

eISSN - 1522-2594

pISSN - 0740-3194

DOI - 10.1002/mrm.1910340404

Subject(s) - in vivo , in vitro , brain abscess , abscess , nuclear magnetic resonance , magnetic resonance imaging , chemistry , alanine , pathology , medicine , nuclear medicine , biology , amino acid , biochemistry , radiology , surgery , physics , microbiology and biotechnology

Five patients, each with a brain abscess, were examined by means of 1 H MR spectroscopic imaging in vivo. The aspirated pus was analyzed in vitro by means of 1D and 2D COSY 1 H MRS. In addition to resonance lines from compounds (lactate, alanine and lipids) often found in the spectra from intracranial tumors, resonance lines were detected from a number of markers of infectious involvement (acetate, succinate, and various amino acids). These results suggest that 1 H MRS in vivo might contribute in establishing noninvasively a differential diagnosis between brain abscess and tumor.

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