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Optimization of T 2 ‐selective binomial pulses for magnetization transfer
Author(s) -
PachotClouard Mathilde,
Darrasse Luc
Publication year - 1995
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910340325
Subject(s) - pulse (music) , magnetization transfer , magnetization , contrast (vision) , nuclear magnetic resonance , sensitivity (control systems) , computational physics , physics , transfer (computing) , magnetic field , materials science , computer science , optics , quantum mechanics , magnetic resonance imaging , parallel computing , medicine , electronic engineering , detector , radiology , engineering
Abstract Accurate rules have been established to build binomial pulses up to fifth order, for selectively saturating protons at any given T 2 with minimum power deposition. Pulse performance and sensitivity to experimental defects have been evaluated; the third order is generally found to be best suited. It is shown, by combining theory and experiment performed at 0.1 T, that matching the saturation pulse to T 2 of the motionally restricted pool is essential to reveal exchange with free water protons. It is emphasized that, to date, lack of magnetization transfer contrast with binomial pulses is due mainly to insufficient RF level available with most MR imaging systems, especially at high magnetic field.