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High contrast and fast three‐dimensional magnetic resonance imaging at high fields
Author(s) -
Lee JingHuei,
Garwood Michael,
Me Ravi,
Adriany Gregor,
Andersen Peter,
Truwit Charles L.,
Uǧurbil Kǎmil
Publication year - 1995
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910340305
Subject(s) - white matter , nuclear magnetic resonance , contrast (vision) , image contrast , physics , magnetic resonance imaging , magnetization transfer , high resolution , optics , geology , medicine , radiology , remote sensing
A new three‐dimensional imaging strategy based on magnetization prepared ultrafast gradient recalled echo technique that demonstrates pronounced T 1 contrast at high fields is introduced. High‐resolution three‐dimensional image sets of human brain showing high contrast between white and gray matter areas are presented. The ratio of contrast‐to‐noise was examined as a function of the relevant parameters in the imaging sequence; calculations based on high‐field T 1 values as well as the experimental data demonstrated that maximal contrast‐to‐noise ratio is attained under the same magnetization preparation conditions both for cortical and subcortical gray matter relative to white matter, leading to approximately equivalent appearance of all gray matter areas in the same image. In addition, the images displayed clear visualization of subtle anatomical structures such as the subthalamic nuclei (ventral tier nuclei, dorsomedial nucleus, and pulvinar) and mammillothalamic tracts.