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Optimized isotropic diffusion weighting
Author(s) -
Wong Eric C.,
Cox Robert W.,
Song Allen W.
Publication year - 1995
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910340202
Subject(s) - isotropy , weighting , anisotropy , diffusion , diffusion mri , attenuation , nuclear magnetic resonance , anisotropic diffusion , tensor (intrinsic definition) , physics , mathematical analysis , computer science , mathematics , optics , geometry , acoustics , magnetic resonance imaging , medicine , radiology , thermodynamics
The authors introduce several sets of time‐efficient gradient waveforms for applying isotropic diffusion weighting in NMR experiments. This creates signal attenuation that depends on the trace of the diffusion tensor and is therefore rotationally invariant. Numerical methods for the calculation of such gradient sets are outlined, and results are shown for isotropic and anisotropic gradient hardware and first order flow moment nulled diffusion weighting gradients. Preliminary experimental results from the human brain validate this new technique.